Applied StemCell  

ASC is a leading gene editing & stem cell therapy CRO/CDMO.

Applied StemCell, Inc. (ASC) is a leading gene editing and stem cell therapy CRO/CDMO company. ASC supports gene editing and stem cell therapy development processes with two high-impact platforms: CRISPR/TARGATT™ genome editing and iPSC (GMP grade). 

As a CDMO, ASC provides complete GMP gene-editing and cell manufacturing as well as banking services completed in a cGMP CMC facility located in Milpitas, California. The expansion of the cGMP facility will be completed in April 2023.

  • GMP Cell Banking
  • GMP iPSC Gene Editing
  • GMP iPSC/MSC Derived Cell Manufacturing
  • Pre-clinical/CRO Services

ASC’s proprietary TARGATT™ technology enables site-specific, stable integration of large DNA fragments into a safe harbor locus more efficiently (~10x better than CRISPR) and faster, with guaranteed transgene expression without the disruption of internal genes and gene silencing. ASC’s TARGATT™ master iPSC line provides an unlimited source of cells of any kind containing therapeutic genes. Application of ASC’s TARGATT™ master iPSC line includes the development of off-the-shelf CAR-iNK/CAR-iT products for immuno cell therapy.

  • TARGATT cell libraries

Brands: ASC is a leading gene editing & cell therapy CRO/CDMO with its cGMP facility located in the CA. Learn more about our GMP-grade iPSCs & cell drug manufacturing capabilities for your pipelines.