Adeno-associated virus (AAV) has been a popular viral vector for gene therapy due to its versatile tropism, its non-pathogenicity and low immunogenicity, as well as its ability to transduce dividing and non-dividing cells
Adenovirus has been a popular viral vector due to its high packaging capacity, high levels of short-term transgene expression, high viral titer, high transduction efficiency, and the inability to integrate into the cell genome
Wildly used in gene therapy applications such as CAR-T therapy, lentivirus is one of the most efficient methods for gene delivery due to its large packaging capacity and its ability to infect non-dividing cells and integrate into the host genome